Research Achievements

Publications

2020

2019

(*  Corresponding Author)

1.  Gou W, Ling CS, He Y, Jiang Z, Fu YQ, Xu FZ, Miao ZL, Sun TY, Lin J, Zhu H, Zhou H, Chen YM*, Zheng JS*. Interpretable machine learning framework reveals robust gut microbiome features associated with type 2 diabetes. Diabetes Care 2020. dc201536. https://doi.org/10.2337/dc20-1536.

 

2. Miao Z, Lin JS, Mao Y, Chen GD, Zeng FF, Dong HL, Jiang ZL, Wang JL, Xiao CM, Shuai ML, Gou WL, Fu YQ, Imamura F, Chen YM*, Zheng JS*. Erythrocyte n-6 polyunsaturated fatty acids, gut microbiota and incident type 2 diabetes: a prospective cohort study. Diabetes Care 2020 Oct; 43(10): 2435-2443. doi: 10.2337/dc20-0631. PMID: 32723842

3. Xu F, Fu Y, Sun T, Jiang Z, Miao Z, Shuai M, Gou W, Ling CW, Yang J, Wang J*, Chen YM*, Zheng JS*. The interplay between host genetics and the gut microbiome reveals common and distinct microbiome features for complex human diseases. Microbiome 2020, 8:145.

 

4. Jiang Z, Sun TY, He Y, Gou W, Zuo LS, Fu Y, Miao Z, Shuai M, Xu F, Xiao C, Liang Y, Wang J, Xu Y, Jing LP, Ling W, Zhou H*, Chen YM*, Zheng JS*. Dietary fruit and vegetable intake, gut microbiota, and type 2 diabetes: results from two large human cohort studies. BMC Med. 2020 Dec 3;18(1):371. doi: 10.1186/s12916-020-01842-0.

​5. Fu YQ, Gou WL, Hu WS, Mao Y, Tian Y, Liang X, Guan Y, Huang T, Li K, Guo X, Liu H*, Li D*, Zheng JS*. Integration of an interpretable machine-learning algorithm to identify early life risk factors of childhood obesity among preterm infants: a prospective birth cohort. BMC Med 2020,18:184.

6. Zheng JS, Luan J,Sofianopoulou E, Imamura F, Stewart ID, Day FR, Pietzner M, Wheeler E, Lotta LA, Gundersen TE, Amiano P, Ardanaz E, Chirlaque MD,  Fagherazzi G, Franks PW,  Kaaks R, Laouali N, Mancini FR, Nilsson PM, N. Charlotte Onland-Moret C, Olsen A, Overvad K, Panico S, Palli D, Ricceri F, Rolandsson O, Spijkerman AMW, María-José Sánchez, Schulze MB , Sala N, Sieri S, Tjønneland A, Tumino R, van der Schouw YT, Weiderpass E, Riboli E, Danesh J, Butterworth AS, Sharp SJ, Langenberg C, Forouhi NG*, Wareham NJ*, Plasma vitamin C and type 2 diabetes: genome-wide association study and Mendelian randomization analysis in European populations. Diabetes Care 2020, dc201328. doi: https://doi.org/10.2337/dc20-1328.

 

7. Zheng JS*, Luan J, Sofianopoulou E, Sharp SJ, Day FR, Imamura F, Thomas E, Lotta LA, Sluijs I, Stewart ID, Shah RL, van der Schouw YT, Wheeler E, Ardanaz E, Boeing H, Dorronsoro M, Dahm CC, Dimou N, El-Fatouhi D, Franks PW, Fagherazzi G, Grioni S, Huerta JM, Heath AK, Hansen L, Jenab M, Jakszyn P, Kaaks R, Kühn T, Kay-Tee Khaw, Laouali N, Masala G, Nilsson PM, Overvad K, Olsen A, Panico S, Quirós JR, Rolandsson O, Rodríguez-Barranco M, Sacerdote C,  Spijkerman AMW, Tong TYN, Tumino R, Tsilidis KK, Danesh J, Riboli E, Butterworth AS, Langenberg C, Forouhi NG* , Wareham NJ*. The association between circulating 25-hydroxyvitamin D metabolites and type 2 diabetes in European populations: A meta-analysis and Mendelian randomisation analysis. PLoS Med.17(10): e1003394. https://doi.org/10.1371/journal.pmed.1003394

8. Zheng JS*, Wahlqvist ML. Regulobiosis: a regulatory and food system-sensitive role for fungal symbionts in human evolution and ecobiology. Asia Pac J Clin Nutr 2020; 29(1):9-15, doi: 10.6133/apjcn.202003_29(1).0002.

9. Zheng JS, Sharp SJ, Imamura F,  Rajiv C, Thomas GE, Marinka S, Sluijs I, van der Schouw YT, Agudo A, Aune D, Barricarte A, Boeing H, Chirlaque MD, Dorronsoro M, Freisling H, Fatoui DE, Franks PW, Fagherazzi G, Grioni S, Gunter MJ, Kyrø C, Katzke V, Kühn T, Khaw KT, Laouali N, Masala G, Nilsson PM, Overvad K, Panico S, Papier K, Quirós JR, Rolandsson O, Redondo-Sánchez D, Ricceri F, Schulze MB, Spijkerman AMW, Tjønneland A, Tong TYN, Tumino R, Weiderpass E, Danesh J, Butterworth AS, Riboli E, Forouhi NG, Wareham NJ. Association of plasma biomarkers of fruit and vegetable intake with incident type 2 diabetes: The EPIC-InterAct case-cohort study in eight European countries. BMJ 2020;370:m2194.

10. Tang J, Wan Y, Zhao M, Zhong H, Zheng JZ*, Feng F*, Legume and soy intake and risk of type 2 diabetes: a systematic review and meta-analysis of prospective cohort studies, Am J Clin Nutr 2020; 111(3):677-688.

11. Tian YY, Ma Y, Fu YQ, Zheng JS*. Application of n-of-1 Clinical Trials in Personalized Nutrition Research: A Trial Protocol for Westlake N-of-1 Trials for Macronutrient Intake (WE-MACNUTR). Current Developments in Nutrition 2020;4(9). doi: 10.1093/cdn/nzaa143

 

12.​ Gou WL, Fu YQ, Yue L, Chen G, Cai X, Shuai ML, Xu FZ, Yi X, Chen H, Zhu Y, Xiao M, Jiang ZL, Miao ZL, Xiao C, Shen B, Wu X, Zhao H, Ling W, Wang J*, Chen YM*, Guo TN*, Zheng, JS*. Gut microbiota may underlie the predisposition of healthy individuals to COVID-19. MedRxiv 2020.04.22.20076091.

1. Zheng JS*, Imamura F, Sharp SJ, Koulman A, Griffin JL, Mulligan AA, Luben R, Khaw KT, Wareham NJ, Forouhi NG*. Changes in plasma phospholipid fatty acids over 13 years and correlates of change: European Prospective Investigation into Cancer and Nutrition-Norfolk Study. Am J Clin Nutr 2019, 109: 1527-34.

2. Zheng JS*, Imamura F, Sharp SJ, van der Schouw YT, Sluijs I, Gundersen TE, Ardanaz E, Boeing H, Bonet C, Gómez JH, Dow C, Fagherazzi G, Franks PW, Jenab M, Kühn T, Kaaks R, Key TJ, Khaw KT, Lasheras C, Mokoroa O, Mancini FR, Nilsson PM, Overvad K, Panico S, Palli D, Rolandsson O, Sieri S, Salamanca-Fernández E, Sacerdote C, Spijkerman AMW, Stepien M, Tjonneland A, Tumino R, Butterworth AS, Riboli E, Danesh J, Langenberg C, Forouhi NG*, Wareham NJ. Association of plasma vitamin D metabolites with incident type 2 diabetes: EPIC-InterAct case-cohort study. J Clin Endocrinol Metab 2019, 104(4): 1293-1303

3.Zheng JS*, Lin JS, Dong HL, Zeng FF, Li D, Song Y, Chen Y*. Association of erythrocyte n-3 polyunsaturated fatty acids with incident type 2 diabetes in a Chinese population. Clin Nutr 2019 38(5):2195-2201

2018

1. Zheng JS*, Chen J, Wang L, Yang H, Fang L, Yu Y, Yuan L, Feng J, Li K, Tang J, Lin M, Lai CQ, Li D*. Replication of a gene-diet interaction at CD36, NOS3 and PPARG in response to omega-3 fatty acid supplements on blood lipids: A double-blind randomized controlled trial. EBioMedicine 2018, 31:150-156.

Before 2018

1. Zheng JS*, Sharp SJ, Imamura F, Koulman A, Schulze MB, Ye Z, Griffin J, Guevara M, Huerta JM, Kroger J, Sluijs I, Agudo A, Barricarte A, Boeing H, Colorado-Yohar S, Dow C, Dorronsoro M, Dinesen PT, Fagherazzi G, Franks PW, Feskens EJM, Kuhn T, Katzke VA, Key TJ, Khaw KT, de Magistris MS, Mancini FR, Molina-Portillo E, Nilsson PM, Olsen A, Overvad K, Palli D, Quiros JR, Rolandsson O, Ricceri F, Spijkerman AMW, Slimani N, Tagliabue G, Tjonneland A, Tumino R, van der Schouw YT, Langenberg C, Riboli E, Forouhi NG*, Wareham NJ. Association between plasma phospholipid saturated fatty acids and metabolic markers of lipid, hepatic, inflammation and glycaemic pathways in eight European countries: A cross-sectional analysis in the EPIC-InterAct study. BMC Med 2017, 15(1): 203.

2. Zheng JS, Lin M, Fang L, Yu Y, Yuan L, Jin Y, Feng J, Wang L, Yang H, Chen W, Tang J, Cai W, Shi M, Li Z, Wang F, Li D*. Effects of n-3 fatty acid supplements on glycemic traits in Chinese type 2 diabetic patients: a double-blind randomized controlled trial. Mol Nutr & Food Res 2016, 60(10):2176-2184.

3. Zheng JS, Parnell LD, Smith CE, Lee YC, Jamal-Allial A, Ma Y, Li D, Tucker KL, Ordovas JM, Lai CQ*. Circulating 25-hydroxyvitamin D, IRS1 variant rs2943641 and insulin resistance: replication of a gene-nutrient interaction in four populations of different ancestries. Clin Chem 2014, 60(1):186-96.

4. Zheng JS, Hu XJ, Zhao YM, Yang J, Li D*. Intake of fish and marine n-3 polyunsaturated fatty acids and risk of breast cancer: meta-analysis of data from 21 independent prospective cohort studies. BMJ 2013, 346:f3706.

5. Zheng JS, Arnett DK, Parnell LD, Smith CE, Li D, Borecki IB, Tucker KL, Ordovas JM, Lai CQ*. Modulation by dietary fat and carbohydrate of IRS1 association with type 2 diabetes traits in two populations of different ancestries. Diabetes Care 2013, 36(9):2621-7.

 

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